【摘要】 建立了六亚甲基-1,6-二氨基甲酸酯热分解产物的HPLC分析方法。以N-甲基苯胺为衍生剂;采用Waters Xbridge C18（4.6 mm×150 mm,5μm）色谱柱,以V_乙腈∶V_水=4∶6为流动相,流速1.0 m L·min^-1;柱温40℃;检测波长205 nm;进样体积10μL。在此条件下,HDI衍生物、六亚甲基-6-氨基甲酸丁酯-1-异氰酸酯（HDUI）衍生物和六亚甲基-1,6-二氨基甲酸丁酯（HDU-B）分离度良好,在测定范围内具有良好的线性关系（r>0.999）、准确性、精密度和重复性。该法可用于热解氨基甲酸酯合成HDI过程中原料HDU-B、热解产物HDUI和HDI的含量分析,操作简单快速。更多还原

【Abstract】 A method for determinating the content ofpyrolysis products of Hexamethylene-1,6-butylcarbamateby HPLC was established.A derived method,which applied N-methyl aniline as the derivative,and Waters-Xbridge C18（ 4.6mm × 150 mm,5μm） column was used in this study.The mobile phase was a two mixture phase consist of acetonitrile and water（ 4:6）.The flow rate was set as 1.0 m L·min^-1,the column temperature was 40 ℃,the detection wavelength was 205 nm and the injection volume was 10 μL.This method exhibited good linearity（ correlation coefficients r>0.999） in the detection range,excellent precision and high stability.With the desirable specificity,sensitivity and repeatability,this method can be used to determine the content of HDU-B,hexamethylene-6-carbamic acid butyl ester-1-isocyanate（ HDUI） and HDI.更多还原