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原发性开角型青光眼房水蛋白含量的检测及其与中医证型关系的研究
Study on the Relationship Between the Contents of Aqueous Humor Protein in Patients with Primary Open Angle Glaucoma and the TCM Syndrome Types
【摘要】 目的探讨原发性开角型青光眼患者眼房水蛋白含量的改变及其与中医辨证分型之间的关系。方法采用溴甲酚绿比色法对128例128只眼原发性开角型青光眼和64例64只眼老年性白内障患者的房水蛋白进行了测定。结果开角型青光眼疾病分类各组及中医证型(肝郁气滞证、痰湿犯目证、肝肾阴虚证)各组均表现为房水白蛋白和总蛋白含量增高,与老年性白内障组相比,各组均有非常显著性差异(P<0.01)。开角型青光眼疾病分类组间比较及中医证型组间比较,房水白蛋白和总蛋白含量亦均有显著性差异(P<0.05)或非常显著性差异(P<0.01)。结论原发性开角型青光眼患者的血-房水屏障功能遭到破坏,房水的粘度增加,房水淤积于眼内。
【Abstract】 Objective To explore the relationship between the protein content in aqueous humor of patients with primary open angle glaucoma and the TCM Syndrome Types. Methods The aqueous humor protein in 128 cases of primary open angle glaucoma and 34 cases of senile cataract patients was measured by bromocresol green colorimetric method. Results The aqueous humor albumin and total protein were increased from open angle glaucoma disease classification groups and the TCM syndrome types(liver depression and Qi stagnation syndrome, phlegm-damp invading the eyes syndrome, liver-kidney Yin deficiency syndrome), compared with the age-related cataract group, each group was statistically significant(P <0.01).There were significant differences in the levels of albumin and total protein in the patients with open angle glaucoma and TCM syndrome types(P<0.05 or P<0.01). Conclusion The blood aqueous barrier function in patients with primary open angle glaucoma was destroyed, the viscosity of aqueous humor increased, and the aqueous humor was deposited in the eyes.
【Key words】 glaucoma; open angle type; aqueous humor protein; liver depression and Qi stagnation syndrome; phlegm-damp invading the eyes syndrome; liver-kidney Yin deficiency syndrome;
- 【文献出处】 湖南中医药大学学报 ,Journal of Hunan University of Chinese Medicine , 编辑部邮箱 ,2016年12期
- 【分类号】R276.7
- 【被引频次】3
- 【下载频次】196