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异嗪皮啶-3-酰胺类化合物的合成与抗肿瘤生物活性研究
Synthesis and Cytotoxic Activity of Some Novel Isofraxidinin-3-amide Derivatives
【摘要】 以异嗪皮啶-3-甲酸为起始原料,通过与不同的氨类化合物缩合得异嗪皮啶-3-酰胺类化合物,从而得到了一类新的异嗪皮啶-3-酰胺化合物,并对其进行了抗肿瘤活性研究。目标化合物结构经MS、~1H NMR确证。
【Abstract】 Using isofraxidin-3-formic acid as the starting material, condensating with different amines, a series of novel isofraxidin-3-amide compounds were obtained. The antitumor activities of these isofraxidin-3-formic compounds were also evaluated. The structure of the target compound was confirmed by MS and ~1 H NMR.
【基金】 辽宁省大学生创新创业训练计划项目;沈阳药科大学大学生创新创业训练计划项目
- 【文献出处】 精细化工中间体 ,Fine Chemical Intermediates , 编辑部邮箱 ,2016年04期
- 【分类号】R914.5;R96
- 【下载频次】88