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早期宫颈腺癌卵巢转移危险因素分析

Analysis of Risk Factors for Ovarian Metastasis from Early Cervical Adenocarcinoma

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【作者】 李明伟姚金娥房昭阮晓红詹雪梅

【Author】 Li Mingwei;Yao Jine;Fang Zhao;Ruan Xiaohong;Zhan Xuemei;Department of Gynecology,the Jiangmen Central Hospital;Department of Oncology,the People’s Hospital of Jiangmen City;

【机构】 江门市中心医院妇科江门市人民医院肿瘤科

【摘要】 目的探讨早期宫颈腺癌卵巢转移的危险因素,为早期宫颈腺癌患者保留卵巢功能提供决策依据。方法回顾性分析111例早期宫颈腺癌(Ⅰa2a期)患者的临床病理资料,分析其卵巢转移的危险因素。结果 111例早期宫颈腺癌患者中,发生卵巢转移9例,转移率8.1%;临床分期、肿瘤直径、宫旁受侵、淋巴结转移、肌层浸润深度、病理分级、宫体受侵及输卵管转移与卵巢转移有关(P<0.05);Logistic回归分析显示:肿瘤大小、宫旁侵犯及输卵管转移与卵巢转移相关(P<0.05)。结论对于早期宫颈腺癌患者,保留卵巢存在一定风险,但对于没有高危因素的早期宫颈腺癌患者,特别是强烈希望保留卵巢功能的年轻患者,充分与患者沟通后可考虑保留卵巢。

【Abstract】 Objective To analyze the risk factors for ovarian metastasis from early cervical adenocarcinoma,to provide a basis for preserving ovarian function in the patients with early cervical adenocarcinoma. Methods The clinicopathologic data of 111 patients with early cervical adenocarcinoma were analyzed retrospectively. The risk factors of ovarian metastasis were subjected. Results Among the 111 patients with early cervical adenocarcinoma(stage Ⅰa2and Ⅱa),9 patients had ovarian metastasis and the transfer rate was 8. 1%. The Pearson Chi square test showed that ovarian metastasis was related to the clinical stage,palace metastasis,oviduct,deep myometrial invasion,tumor size,pathological grading,uterine body invasion and pelvic lymph node metastasis( P < 0. 05). Logistic regression analysis showed that ovarian metastasis was related to the tumor size,palace metastasis and oviduct metastasis( P < 0. 05). Conclusion There are some risks for early cervical adenocarcinoma; the risk factors for ovarian metastasis from young patients who want to keep ovaries must be carefully assessed.

  • 【文献出处】 肿瘤基础与临床 ,Journal of Basic and Clinical Oncology , 编辑部邮箱 ,2016年04期
  • 【分类号】R737.33
  • 【被引频次】4
  • 【下载频次】93
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