【摘要】 目的探讨宫颈小细胞癌(SCCC)的临床病理特征。方法回顾性分析10例SCCC患者的临床病理特征及预后。结果 10例SCCC患者中,Ⅰb期7例,Ⅱb期1例,Ⅲb期1例,Ⅳ期1例。免疫组化染色结果显示,CK、EMA、Syn、NSE、Cg A、CD56的阳性表达率分别为80.0%、70.0%、70.0%、80.0%、40.0%、90.0%。7例Ⅰb期患者随访3~36个月,1例失访,3例死亡,余3例生存;1例Ⅱa期患者,随访24个月,生存;1例Ⅲb期患者确诊6个月后死亡;1例Ⅳ期患者确诊7个月后死亡。结论 SCCC恶性度高,侵袭性强,预后差,病理形态学与胃肠道和肺的小细胞癌相似;早发现、早诊断、早治疗可提高患者的生存率。更多还原

【Abstract】 Objective To study the clinicopathological characterises of small cell carcinoma of the uterine cervix( SCCC). Methods The clinicopathological characterises and the factors for prognosis about 10 patients with SCCC were analyzed retrospectively. Results Among these 10 patients,there were 7 patients with Ⅰb,1 patients withⅡb,1 patients with Ⅲb,and 1 patients with Ⅳ. The percentages of SCCC with immunoreactivity were,the positive rates of CK,EMA,Syn,Cg A,CD56 were 80. 0%,70. 0%,70. 0%,40. 0%,90. 0%. 7 patients with Ⅰb were followed-up for 3 months to 36 months,1 patient was lost,and 3 patients were died,3 patients were alive; 1 patient with Ⅱa which followed-up for 24 months was alive; 1 patients with Ⅲb was died after diagnosed for 6 months;1 patients with Ⅳ was died after diagnosed for 7 months. Conclusion SCCC which pathological morphology was similar to small cell carcinoma of stomach and lung was a kind of malignant tumor,it is aggressive and with poor prognosis. So early detection,early diagnosis and early treatment are crucial to improve the cure rate of patients.更多还原