【摘要】 目的探讨胸段食管鳞癌中各临床病理因素对淋巴结转移度的影响作用。方法回顾性分析汕头大学医学院第一附属医院心胸外科手术治疗的60例胸段食管鳞癌患者的临床病理资料,比较不同的肿瘤部位、肿瘤长度、分化程度、浸润程度、TNM分期等因素之间的淋巴结转移度的差异。结果全组60例患者共清扫1 198个淋巴结,转移淋巴结55个,总淋巴结转移度4.59%。随着病变越靠下段、分化程度越低、病理分期越晚,淋巴结转移度呈显著上升趋势(P<0.05);肿瘤长度、浸润程度与淋巴结转移度无关(P>0.05)。结论肿瘤部位、分化程度及TNM分期可作为预测食管癌淋巴结转移状态的重要因素,这些因素对指导术中淋巴结清扫、术后综合治疗以及评估预后具有重要的意义。更多还原

【Abstract】 Objective To explore the influence of clinicopathological features on lymph nodes metastasis ratio in the cases of thoracic esophageal squamous cell carcinoma. Methods A retrospective study was made on the clinicopathological materials for 60 patients with radical resection of thoracic esophageal squamous cell carcinoma. Meanwhile,the analysis was made on the correlation between clinicopathological features(which including tumor site,tumor length,differentiation degree,infiltration degree and TNM staging) and lymph nodes metastasis ratio. Results Total of 1198 lymph nodes was removed in 60 patients and metastases existed in 55 lymph nodes,thus the general lymph nodes metastasis ratio was 4. 59%. The lower differentiation degree,the lower tumor site and the higher TNM staging could result in an increasing of lymph nodes metastasis ratio(P < 0. 05). However,there were no significant relation between tumor length,infiltration degree and lymph nodes metastasis ratio(P > 0. 05). Conclusion Tumor site,differentiation degree and TNM staging can be regarded as the important predictors of lymph node metastasis for patients with esophageal carcinoma,and these factors may play important roles in lymph node dissection,postoperative comprehensive treatment and prognostic assessment.更多还原