【摘要】 采用"两浴-溶剂热法"制备了NaYF₄∶Yb³⁺,Er³⁺上转换发光纳米粒子（UCNP）,利用葡萄糖在苷化温度下置换UCNP表面的油酸,制得表面包被葡聚糖的亲水性UCNP。进一步通过NaIO₄氧化表面葡聚糖,获得了醛基化UCNP。采用TEM及光纤光谱仪等对修饰前后材料的形貌、发光特性进行了表征。优化实验表明0.5mol/mL葡萄糖在130℃下包被葡聚糖48h效果最好,包被后的UCNP在水相中分散良好且可在超过2个月内保持原有发光强度的75%。通过调节NaIO₄用量及氧化反应时间可以调控表面醛基修饰量。更多还原

【Abstract】 Up-conversion nanocrystals composite NaYF4∶Yb³⁺,Er³⁺（UCNP）was synthesized by"two baths-solvo thermal"method.Oleic acid on the surface of UCNP was replaced by hydrophilic glucosan under hydrothermal glycosidation temperature of glucose.The hydroxyl of glucosan was then converted to aldehyde group by NaIO₄ oxidation.Morphology and fluoro luminescent properties of UCNPs were studied using TEM and fiber optic spectrometer.Coating temperature,concentration of glucose and incubation time were optimized at 130℃,0.5mol/mL and 48 h,respectively.The coated UCNP could be well dispersed in water and 75% of the original luminescence was maintained for more than 2months.It was also found that the amount of aldehyde group could be controlled by changing the concentration of NaIO₄ and oxidation duration.This simple and reliable surface modification approach provided a new way to biological application of UCNP.更多还原