【摘要】 以对甲氧基苯胺和固体三光气为起始原料,制得4-甲氧基苯异氰酸酯(1);1与取代胺(2a~2i)反应合成了9个新型的1-取代-3-(4-甲氧基苯基)脲衍生物(3a~3i),其结构经1H NMR,13C NMR和HR-MS表征。用黄瓜子叶扩张法和小麦芽鞘法研究了3a~3i的生物活性。结果表明:1-(4-甲氧基苯基)-3-[3-(三氟甲基)苯基]脲(3c)的生长素活性最好。在用药浓度为10 mg·L-1时,3c的生长素活性为29.8%,优于β-吲哚乙酸(29.3%)。更多还原

【Abstract】 1-Isocyanato-4-methoxybenzene（ 1） was prepared by the reaction of methoxyaniline with triphosgene. Nine novel 1-substituted-3-（ 4-methoxy-phenyl） urea derivatives（ 3a 3i） were synthesized by the reaction of 1 wtih substituted amines（ 2a 2i）. The structures were characterized by ¹ H NMR,¹³C NMR and HR-MS. The biological activities of 3a 3i were investigated by cucumber cotyledon expansion method and wheat sprout and sheath method. The results showed that 1-（ 4-methoxyphenyl）-3-[3-（ trifluoromethyl） phenyl]urea（ 3c） exhibited best biological activities with auxin activity of 29. 8% at dosage of 10 mg·L-1,better than β-indoleacetic acid（ 29. 3%）.更多还原