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国产玛咖小鼠免疫调节作用的实验研究

Study on Immune Regulation Effect of Domestic Maca in Mice

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【作者】 王彦武赵鹏高玉秋彭亮覃辉艳梁慧莉

【Author】 WANG Yan-wu;ZHAO Peng;GAO Yu-qiu;PENG Liang;QIN Hui-yan;LIANG Hui-li;Guangxi Zhuang Autonomous Region Center for Disease Prevention and Control;

【机构】 广西壮族自治区疾病预防控制中心

【摘要】 目的探讨国产玛咖对小鼠的免疫调节作用。方法分别以190、380、760mg·kg-1的玛咖经口给予小鼠连续灌胃30d后,进行各项免疫指标的测定。结果玛咖剂量组与对照组比较能促进小鼠脾淋巴细胞增值转化作用及小鼠的迟发型变态反应(P<0.05),促进小鼠的抗体生成细胞增加(P<0.05,P<0.01),提高小鼠的单核巨噬细胞吞噬能力及小鼠的NK细胞活性(P<0.05)。结论国产玛咖具有增强免疫力的功能。

【Abstract】 OBJECTIVE To explore the effect of domestic Maca on the function of immunoregulation. METHODS The mice were feed with Maca at the doses of 190,380 and 760mg·kg- 1for 30 days,then 7 indexes of immune function were measured to judge the effect of Maca on immune system. RESULTS The results of the test groups in comparison with the control group showed that transformation and proliferation of splenic lymphocyte were enhanced( P < 0. 05); Promote mice late hairstyle allergy( P < 0. 05); increase the quantity of the mice antibody-producing cell( P < 0. 05,P < 0. 01); The mononuclear macrophage phagocytic activity were increased( P <0. 05); To improve the activity of NK cells in mice( P < 0. 05); CONCLUSION The results indicated that domestic Maca could enhance several immunologic functions of mice.

【关键词】 国产玛咖小鼠免疫调节
【Key words】 Domestic MacaMiceImmunoregulation
【基金】 广西科技基础条件平台建设项目(12-97-18)
  • 【文献出处】 海峡药学 ,Strait Pharmaceutical Journal , 编辑部邮箱 ,2016年08期
  • 【分类号】R285.5
  • 【被引频次】5
  • 【下载频次】137
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