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头孢噻肟钠舒巴坦钠对小婴儿感染的治疗效果观察

Effect of Infant with Infection Treated with Cefotaxime Sodium and Sulbactam Sodium

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【作者】 李国华李秀琼罗敏叶妙珍邵秀敏陈琼梁道喜陈敬国

【Author】 LI Guo-hua;LI Xiu-qiong;LUO Min;YE Miao-zhen;SHAO Xiu-min;CHEN Qiong;LIANG Dao-xi;CHEN Jing-guo;Department of pediatrics,Qingxi hospital of Guang Dong province Dongguan city;

【机构】 广东东莞市清溪医院儿科

【摘要】 目的探讨头孢噻肟钠舒巴坦钠对小婴儿感染的疗效。方法将140例小婴儿感染患儿随机分成两组,治疗组72例,应用头孢噻肟钠舒巴坦钠治疗,对照组68例,应用青霉素钠治疗,将两组资料进行统计学分析比较。结果①:治疗组有效率90.2%,细菌清除率91.4%,与对照组有效率64.3%,细菌清除率65.1%相比有显著区别(P<0.05)。②:治疗组对表葡菌,G-杆菌清除率分别为80.7%,86.7%,与对照组相比有显著差异(P<0.05)。③:治疗组对金葡菌的清除率为50%,对照组为40%,两组差异无显著性(P>0.05)。结论头孢噻肟钠舒巴坦钠在小婴儿感染的疗效明显优于青霉素钠,且在小婴儿的用药十分安全。

【Abstract】 OBJECTIVE To investigate the effection of infant with infection that treated with Cefotaxime Sodium and Sulbactam Sodium. METHODS 140 infant with infection were divided randomly into two groups:the treated group with Cefotaxime Sodium and Sulbactam Sodium therapy( n = 72),the control group with penicillin-G therapy( n= 68),and then analyzed the datum of the two groups. RESULTS ①The effective rate was 90. 2%,baceria-cleaning rate was 91. 4%,it’s more effective than control patient’s. ②A statistical comparison between two groups was significant with regard to the rates of cleaning staphylococcus epidermidis,gram-negative bacilli,The bacteria-cleaning rates were respectively 80. 7%,86. 7%( P < 0. 05). ③The effective rate was similar between the Cefotaxime Sodium and Sulbactam Sodium and Penicillin-G to the infection by staphylococcus aureus. CONCLUSION The effection of yonger infat patients with infection that treated with Cefotaxime Sodium and Sulbactam Sodium was better than that treated by Penicillin-G.

  • 【文献出处】 海峡药学 ,Strait Pharmaceutical Journal , 编辑部邮箱 ,2016年03期
  • 【分类号】R725.1
  • 【被引频次】1
  • 【下载频次】43
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