【摘要】 藏药蕨麻是蔷薇科委陵菜属植物鹅绒委陵菜(Potentilla anserinea L.)的根,主要分布于北半球的温带、寒带和高寒地区,在中国主要分布于青海、甘肃、西藏等地。蕨麻作为药食两用植物,已有1200多年的药用历史。蕨麻主要含有多糖、甾类、三萜类、黄酮类、酚酸类和香豆素类化合物等多种化学成分。中医学研究表明,蕨麻具有健胃补脾、生津解渴、益气补血等功能。蕨麻在藏药中应用广泛,其中多糖作为其主要活性成分具有调节免疫力、抗低氧、抗氧化、抗肿瘤及保肝作用。本文主要综述蕨麻多糖的药理活性及其研究进展,以期为其深入研究和进一步开发利用提供参考。更多还原

【Abstract】 The genus Potentilla are a member of Rosaceae family. The root of P. anserina L. is an important medicinal plant in Chinese Tibetan medicine and known as‘jue ma’in traditional Chinese medicine(TCM),which is mainly distributed in temperate,frigid and alpine zones of the northern hemisphere. In China,it is mainly distributed in Qinghai,Gansu provinces and Tibet Autonomous Region. This genus mainly contains polysaccharides,steroids,triterpenes,flavonoids,phenolic acids and coumarin compounds. The root of P. anserina has been used as both food and medicine over 1200 years. In TCM,it is suggested that the functions and indications of P. anserina be various,such as supplementing the spleen and fortifying the stomach,promoting the production of body fluid and relieving thirst,invigorating the vital energy and nourishing the blood. P. anserina is widely used in Chinese Tibetan Medicine,and polysaccharide extracted from its rhizomes is one of the main constituents possessing the pharmacology of immunomodulatory activity,anti-oxidation,anti-hypoxia,anti-tumor and protective effect on liver injury. This article reviews the recent research progresses in the pharmacology of P. anserina polysaccharide(PAP),so as to lay the foundation of basic researches for further investigation and could provide the instruction for the further development and utilizition of this plant.更多还原