【摘要】 目的探讨血清同型半胱氨酸(Hcy)、超敏C-反应蛋白(hs-CRP)水平变化对诊断妊娠高血压的意义;评价Hcy、hsCRP测定对妊娠高血压的临床价值。方法选择妊娠期高血压疾病患者150例作为实验组,包括轻度妊娠期高血压49例、中度妊娠期高血压51例,重度妊娠期高血压50例;并随机选取同期正常孕晚期孕妇50例作为对照组,测定血浆Hcy及hs-CRP水平。结果妊娠高血压疾病组血清Hcy及hs-CRP水平明显升高,与对照组相比,差异有统计学意义(P<0.01);重度妊娠高血压疾病患者则明显高于中度和轻度妊娠高血压疾病患者组,差异有统计学意义(P<0.01)。结论动态监测孕妇血清中Hcy及hsCRP水平有利于妊娠高血压疾病的预防及早期治疗,可以评价本病的病情发展及预后。更多还原

【Abstract】 Objective To explore the significance of serum homocysteine(Hcy)and high sensitive C-reactive protein(hs-CRP)levels change on the diagnosis of pregnancy induced hypertension(PIH)and to evaluate the clinical value of the Hcy and hs-CRP determination on PIH.Methods 150 patients with PIH were selected as the experimental group,including 49 cases of mild PIH,51 cases of moderate PIH and 50 cases of severe PIH;contemporaneous 50 normal late pregnant women were randomly selected as the control group.The serum Hcy and hs-CRP levels were detected.Results The serum Hcy and hs-CRP levels in the PIH group were significantly increased compared with control group,the difference was statistically significant(P<0.01);the serum Hcy and hsCRP levels in the severe PIH group were significantly higher than those in the moderate and mild PIH groups,the differences were statistically significant(P<0.01).Conclusion Dynamically monitoring serum Hcy and hs-CRP levels in pregnant women is conducive to the prevention and early treatment of PIH and can evaluate the disease progression and prognosis of PIH.更多还原