【摘要】 目的了解北京市西城区麻疹疑似病例的血清学检测情况,为麻疹的监测与预防提供依据。方法分析2011—2014年北京市西城区麻疹疑似病例200份血标本的检测结果及年龄分布情况。结果 2011—2014年麻疹疑似病例血清学检测阳性率为32.50%(65/200);各年份血清学检测阳性率分别为12.00%、4.35%、33.90%和44.09%;不同年份血清学检测阳性率比较,差异有统计学意义(P<0.001)。200例麻疹疑似病例中,<5岁组65例,血清学检测阳性率为35.38%;>24岁组97例,血清学检测阳性率为34.02%;31例接种疫苗,接种率为15.50%;IgM抗体阳性病例疫苗接种率(3.08%)低于IgM抗体阴性病例(21.48%),差异有统计学意义(P<0.001)。结论 2011—2014年北京市西城区麻疹血清检测阳性率2012年降低,然后逐年上升,5岁以下儿童通过麻疹疫苗免疫接种麻疹将得到控制,为实现消除麻疹的计划,有效控制和预防成人麻疹发病具有重要意义。更多还原

【Abstract】 Objective To understand the serological detection of suspected measles cases in Xicheng District of Beijing,and provide basis for monitoring and prevention of measles.Methods Detection results of 200 blood specimens and age distribution of suspected measles cases in Xicheng District of Beijing in 2011-2014 were analyzed.Results The positive rate of serological detection of suspected measles cases in 2011-2014 was 32.50%(65/200);positive rates in each year were 12.00%,4.35%,33.90%,and 44.09% respectively;there was significant difference in the positive rate of serological tests in different years(P<0.001).Of 200 cases,65 were<5 years old,and97 were>24 years old,positive rates of serological detection were 35.38% and 34.02% respectively;31 cases(15.50%)received vaccination of measles;vaccine coverage rate in IgM antibody positive cases was lower than IgM antibody negative cases(3.08% vs 21.48%,P<0.001).Conclusion Positive rate of serological detection decreased in 2012,then increased year by year,for children under 5 years,measles are controlled by immunization with measles vaccine,in order to achieve the goal of eliminating measles effectively,control and prevention of adult measles is of great significance.更多还原