【摘要】 利用生物复合法制备细菌纤维素/无纺布复合材料(BC/N),并对其结构、含水率、失水率、力学性能进行测试,结合体外细胞培养对材料进行生物安全性研究,并通过原位复合法制备载Ag的BC/N材料。结果发现,细菌纤维素(BC)与无纺布(Non)实现良好的复合,复合材料的含水率从410%提升到1 018%,失水率从82.39%降至48.07%,有效提高了复合材料的含水率及保湿性;BC/N的拉伸强度和断裂伸长率较BC和Non有明显提高;MTT结果显示该材料具有良好的生物相容性;抗菌实验表明载Ag的BC/N具有极佳的抗菌性,对大肠杆菌和金黄色葡萄球菌的抑菌率最大可达99.96%,99.93%。因此,该材料有望在医用敷料领域得到广泛应用。更多还原

【Abstract】 Bacterial cellulose/nonwoven composite was prepared by biological composition method.The structure,moisture content,moisture loss rate and mechanical properties were studied.Besides,biological safety was also studied by L929 cell culture in vitro.And the antibacterial BC/N-Ag composites were prepared by in situ composite.The results showed that bacterial cellulose(BC)and nonwoven(Non)achieved good composite.And the moisture content of bacterial cellulose/nonwoven composite increased from 410%to 1 018%,the water loss rate decreased from 82.39% to 48.07%.The composite enhanced the moisture content and water holding capacity of bacterial cellulose/nonwoven composite.And both tensile strength and elongation at break were higher than BC and Non.MTT showed that BC/N had good biocompatibility.Antibacterial results showed that BC/N-Ag had excellent antibacterial properties,and the highest antibacterial rate against escherichia coli staphylococcus aureus reached 99.96% and 99.93%respectively.Therefore,this material was expected to be widely used in the field of medical dressing.更多还原