【摘要】 目的探讨血浆致动脉硬化指数(AIP)与脑卒中关系。方法选取200例脑卒中患者和200例无脑血管疾病患者或健康人,分析体质指数、血压、血脂、AIP与脑卒中相关性。结果两组中收缩压(SBP)、舒张压(DBP)、血浆总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、和AIP差异均有统计学意义(均P<0.05)。多元回归分析显示SBP、TG、LDL-C、HDL-C是AIP的影响因素(P<0.01或0.05)。AIP异常者发生脑卒中危险性是AIP正常者24倍。结论 AIP反映了脑卒中患者脂蛋白代谢紊乱,可用于评估脑卒中风险。更多还原

【Abstract】 Objective To study the correlation between atherogenic index of plasma(AIP) and stroke. Methods The correlation between body mass index, blood pressure, plasma lipids, AIP and stroke was analyzed in 200 stroke patients and 200 non-stroke patients or healthy controls. Results Systolic blood pressure(SBP), diastolic blood pressure(DBP), total cholesterol(TC), triglyceride(TG), high density lipoprotein cholesterol(HDL-C), low-density lipoprotein cholesterol(LDLC) and AIP were different between two groups(P<0.05). Multivariate regression analysis showed that SBP, TG, HDL-C and LDL-C had impacts on AIP(P<0.01 or 0.05). The risk of stroke was 24-fold in patients with abnormal AIP compared with those with normal AIP. Conclusion AIP reflects the metabolic disturbance of lipoprotein in patients with stroke, which is useful to evaluate the risk of stroke.更多还原