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多点射频微创治疗三叉神经痛的临床研究

Clinical study on trigeminal neuralgia treatment with minimally invasive multipoint radiofrequency thermal coagulation

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【作者】 张清彬邓力张颖邓末宏常世民何霞

【Author】 ZHANG Qing-bin;DENG Li;ZHANG Ying;DENG Mo-hong;CHANG Shi-min;HE Xia;Key Laboratory of Oral Medicine,Guangzhou Institute of Oral Disease,Stomatology Hospital of Guangzhou Medical University;

【机构】 广州医科大学附属口腔医院·广州口腔疾病研究所·口腔医学重点实验室武汉大学口腔医院颞下颌关节外科首都医科大学附属北京友谊医院口腔颌面外科

【摘要】 目的观察三叉神经干及外周支多点射频热凝术治疗三叉神经痛的临床疗效。方法选取确诊为三叉神经痛的患者180例,按照随机原则将所有入选患者分为治疗组60例,对照组Ⅰ60例,对照组Ⅱ60例。治疗组行三叉神经干及外周支多点射频热凝术治疗,对照组Ⅰ行单纯三叉神经半月节射频热凝治疗,对照组Ⅱ行三叉神经干及外周支封闭治疗,治疗后随访24个月,对3组疗效进行对比分析。结果治疗组、对照组Ⅰ与对照组Ⅱ的总有效率分别为100%、100%、60%,治疗组术后疼痛程度视觉模拟评分结果与对照组Ⅰ差异无统计学意义(P>0.05),治疗组术后疼痛程度视觉模拟评分结果明显小于对照组Ⅱ,差异有统计学意义(P<0.05)。治疗组并发症比对照组Ⅰ少,治疗组与对照组Ⅰ在相同随访时间内复发率差异无统计学意义(P>0.05)。结论三叉神经干及外周支的多点射频热凝术治疗三叉神经痛疗效显著,微创,并发症少,复发率低,安全性高。

【Abstract】 Objective To observe the clinical efficacy of multipoint radiofrequency thermal coagulation on trigeminal neuralgia management. Methods 180 patients diagnosed as primary trigeminal neuralgia were included in this study.The patients were randomly divided into three groups,60 patients in treatment group,60 patients in the first control group and 60 patients in second control group respectively. Multipoint radiofrequency ablation therapy was utilized in the treatment group,radiofrequency thermal coagulation therapy on trigeminal ganglion was applied in the first control group and patients in second control group were treated by nerve block therapy. Then the curative effect of the three groups after the treatment was compared and analyzed. Results To the curative effects,the VAS score showed insignificant difference between treatment group and the first control group( P > 0. 05),while an significant difference between treatment group and the second control group( P < 0. 05). To the complications concerned,higher occurrence was found in the first control group. There was no significant difference between the treatment group and the first control group in the recurrence rate( P > 0. 05). Conclusion The minimally invasive multipoint radiofrequency ablation on the treatment of trigeminal neuralgia has significant effect with fewer complications and higher patients safety.

【基金】 广东省医学科研基金(A2013294)
  • 【文献出处】 口腔疾病防治 ,Journal of Prevention and Treatment for Stomatological Diseases , 编辑部邮箱 ,2016年02期
  • 【分类号】R745.11
  • 【被引频次】8
  • 【下载频次】148
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