【摘要】 选用新型双二茂铁亚胺环钯配合物(Fc2C NPh)Pd Cl PPh3(Fc=Ferrocenyl,Ph=Phenyl)作为催化剂,通过碘代二茂铁作为反应底物,进行Suzuki-Miyaura交叉偶联反应,以良好产率,合成了一系列具有特殊取代基的二茂铁衍生物(1~9).优化了制备二茂铁衍生物的交叉偶联反应条件,考察了底物适应范围,给出了优化合成路线,推测了催化反应机理.结果表明,选用的环钯配合物催化剂对潮气和空气不敏感,具有催化剂用量少(痕量)、催化反应活性高、底物适应范围宽等优点,是制备二茂铁衍生物的理想催化剂.更多还原

【Abstract】 A series of ferrocenyl derivatives with special substituent( 1—9) in middle to excellent yields was synthesized by Suzuki-Miyaura cross-coupling reaction using new diferrocenylimine cyclopalladated complex( Fc2 C = NPh) Pd Cl PPh3( Fc = Ferrocenyl,Ph = Phenyl) as catalyst and Fc-I as reactant. The cross-coupling reaction conditions were optimized and the substrate scope was investigated,and a synthetic route was given for preparing ferrocenyl derivatives and the catalytic reaction mechanism was deduced. The results show that the complex catalyst highlights the features of high catalytic activity,trace catalyst loading,wide substrate scope,excellent reaction efficiency and insensitive to air and moisture for synthesizing ferrocenyl derivatives.更多还原