Objective To investigate the correlation between HBV DNA and tumor markers in patients with hepatitis B( HB) infection and liver cirrhosis,guidance for early diagnosis of liver cancer. Methods Sixty patients with hepatitis B cirrhosis and 60 cases of liver cancer were selected as cirrhosis group and liver cancer group,respectively. The HBV DNA was detected by PCR method,and AFP- L3 and GP73 were detected using enzyme- linked immunoassay.Results The HBV DNA,AFP- L3 and GP73 expression were significantly lowe...
【基金】
河北省医学科学研究重点课题计划(编号:20120290)
【更新日期】
2017-01-31
【分类号】
R735.7;R512.62;R575.2
【正文快照】
任丘062552)Corresponding author:MU Li-qin,E-mail:1456949633@qq.com乙型肝炎(以下简称乙肝)病毒[1](hepatitis B vi-rus,HBV)的活跃复制是乙肝肝硬化发生和发展的高危因素,而乙肝肝硬化的结局大多为原发性肝细胞癌。甲胎蛋白异质体3(AFP-L3)和高尔基蛋白73(GP73)是近年来研