【摘要】 目的观察不同方式补充铁剂对维持性血液透析并肾性贫血患者的影响,探讨最好的补铁给药途径。方法将90例血液透析患者随机分为血泵前静脉滴注组(静滴组)和血泵后肝素泵静脉注射组(静推组)各45例,两组在血透中分别使用血泵前静滴蔗糖铁和血泵后肝素泵静推蔗糖铁,均为每周1次,每次100 mg,总量为1 000mg。观察两组患者疗效、透析器凝血、血透机空气报警的发生率。结果两组患者用药治疗1个疗程后,患者的血红蛋白(HB)、红细胞压积(HCT)和血清铁蛋白(SF)都比治疗前有了很大的提高,差异有统计学意义(P<0.001);两组患者各项指标提高的程度差异无统计学意义(P>0.05);静推组在血透机空气报警、透析器凝血次数发生率以及用药相关费用明显低于静滴组(P<0.01)。结论静推补充铁剂不仅能合理应用资源,减少护士的工作量,而且能保证血液透析的顺利进行。更多还原

【Abstract】 Objective To observe the effect of different schedules for iron supplementation in renal anemia patients undergoing hemodialysis in order to find out a efficient,safe and convenient iron supplementation method for these patients.Methods 90 patients with maintenance hemodialysis were divided into two groups,arterial end pump intravenous iron sucrose group and intravenous heparin pump intravenous injection group once every week,100 mg each time and with a total volume of 1 000 mg. The patients,effects,dialyzer coagulation and the hemodialysis machine air alarm were tested in the two groups,and then compared between the groups. Results Compared to pre-treatment,hemoglobin,HCT and the serum ferritin was increased significantly two weeks after that( P < 0. 001),but the increases in the indexes within each group were no significant( P > 0. 05). The hemodialysis machine air alarm,dialyzer coagulation times and the related costs in the intravenous group are lower than that in the intravenous drip group( P < 0. 01). Conclusion Intravenous heparin pump intravenous iron sucrose can not only make the best use of resources and reduce consumption,but also can improve the safety of medication.更多还原