【摘要】 目的:探讨手足口病对红细胞功能的影响。方法:收集2014年在我院住院的手足口病患儿,按照病情分组,行红细胞、血清铁和血气分析检测。结果:随着手足口病病情的加重,血液中红细胞数目、红细胞平均体积和血红蛋白含量有增加的趋势(P>0.05),血清铁含量也从1期的(5.60±4.18)μmol/L增加到4期的(13.13±4.70)μmol/L。同时,Pa O2由1期的(91.30±19.50)mm Hg下降到4期的(80.71±27.57)mm Hg;p H由1期的7.42±0.04下降到4期的7.33±0.19;Pa CO2由1期的(31.40±4.32)mm Hg增加到4期的(36.43±19.03)mm Hg;血乳酸含量由1期的(1.47±0.90)mmol/L增加到4期的(3.67±3.10)mmol/L。结论:红细胞可能参与了手足口病的发生发展,随着手足口病病情的加重,红细胞铁利用和携氧功能障碍也加重。更多还原

【Abstract】 Objective: To investigate the change of red blood cell function in children with hand-foot-mouth disease. Methods:Children with hand-foot-mouth disease,admitted by our hospital from January 2014 to December 2014,were divided according to the condition. Erythrocyte,serum iron and blood gas were detected. Results: Erythrocyte count,mean corpuscular volume and hemoglobin level increased with illness aggravating and serum iron also increased from( 5. 60 ± 4. 18) μmol / L in stage 1 to( 13. 13 ± 4. 70) μmol / L in stage 4. Meanwhile,Pa CO2 and blood lactic acid were respectively raised from( 31. 40 ± 4. 32) mm Hg and( 1. 47 ± 0. 90) mmol / L in stage1 to( 36. 43 ± 19. 03) mm Hg and( 3. 67 ± 3. 10) mmol / L in stage 4,but PO2 and p H value decreased( 91. 30 ± 19. 50) mm Hg and 7. 42 ± 0. 04 in stage 1 to( 80. 71 ± 27. 57) mm Hg and 7. 33 ± 0. 19 in stage 4. Conclusion: Erythrocyte might participate in the genesis and development of hand-foot-mouth disease. The oxygen carrying function and iron utilization function are also injury with illness aggravating.更多还原