Objective To explore the role of F10 gene in regulating cell cycles of choriocarcinoma cells and the underlying mechanisms. Methods Using untreated cells as the control, JAR cells with F10 gene silencing or stable F10 over- expression were examined for cell cycle changes by flow cytometry(FCM) and for expressions of cyclinand cyclin- dependent kinase(CDKs) with Western blotting and immunofluorescence technique. Results JAR cells over- expressing F10 gene showed reduced duration of cell cycle compared with u...
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