Objective To determine the effect of propofol on the proliferation of neural precursor cells( NPCs) of piriform cortex in neonatal mice. Methods Fifteen healthy 7-day-old C57 mice from the same litters were randomly divided into 3 groups,that is,control group,low-( 30 mg / kg) and high-dose propofol groups( 60 mg / kg). The animals of the 2 latter groups were treated with corresponding drugs on postnatal days 7( P7) by intra-peritoneal injection,while those of the control group were injected with the same v...