Mission planning is one of key technologies for Unmanned Aerial Vehicle( UAV) cooperative combat. For the task of suppressing the enemy's aerial-defense firepower,we established a mission planning model for multi-UAV cooperative attacking multiple ground targets by taking terrain and threat distribution,firepower resource needed to destroy the targets,and damage probability of UAVs into consideration. A parallel Genetic Algorithm and Particle Swarm Optimization( GAPSO) algorithm was proposed to resolve this...