【摘要】 目的应用冠状动脉CTA评估肥厚型心肌病伴发稳定性心绞痛患者冠状动脉狭窄情况。方法回顾性分析2011.6-2014.6间55例稳定性心绞痛症状的肥厚型心肌病患者,选取无肥厚型心肌病但冠状动脉CTA表现为冠状动脉狭窄(6个月内)患者55例作为对照组。所有病例由2名经验丰富放射医师采用双盲法进行独立阅片,管腔狭窄>70%为严重冠状动脉狭窄,管腔<50%为轻度冠状动脉狭窄,管腔50-70%为中度冠状动脉狭窄。结果肥厚型心肌病患者中度或重度冠状动脉狭窄发生率明显低于对照组(P<0.01),同时肥厚型心肌病患者单支中度冠状动脉狭窄发生率明显低于对照组(P<0.01)。肥厚型心肌病患者左前降支中度或重度狭窄明显低于对照组(P=0.02)。肥厚型心肌病组平均深度是5.0±2.4mm、平均宽度是27.5±13.4mm;对照组平均深度为2.7±1.2mm平均宽度为8.8±3.4mm,P<0.01。结论冠状动脉CTA应成为检查肥厚型心肌病患者表现为稳定性心绞痛是否冠状动脉狭窄首选检查方法。更多还原

【Abstract】 Objective To assessment of patients with HCM and stable anginal symptoms incidence of epicardial coronary artery. Methods Retrospective analysis 2011.6-2014.6 55 hypertrophic cardiomyopathy patients Age-and gender-matched patients without HCM referred for CCTA because of similar symptoms over a 6-month period were used as controls. The coronary arteries were evaluated independently by 2 blinded observers, and any luminal narrowing was scored quantitatively as follows:>70% severe; 50%- 70% moderate; <50% mild; and none. Resultsesults the incidence of moderate or severe coronaryartery stenosis was significantly lower in patients with HCM compared to the control group(P<0.0001). Also,severe stenosis alone was significantly lower in the HCM group compared to controls(P<0.0001). the incidence of moderate or severe LAD stenosis was significantlylower in the HCM patients than in the controls(P<0.002). ConclusionCCTA should be considered as a first-line investigation for HCM patients with stable anginal symptoms in epicardial coronary artery stenosis.更多还原