【摘要】 目的应用实时三维超声心动图（RT-3DE）评价风湿性心脏病单纯二尖瓣狭窄（MS）患者左房功能。方法应用RT-3DE测量30例风湿性心脏病MS患者及50例正常对照左房最大容积(LAV_max)、左房最小容积(LAV_min)、左房收缩前容积(LAV_pre),计算左房总射血容量（TASV）、左房被动射血容量（PASV）、左房主动射血容量（AASV）、左房扩张指数（LAEI）、左房整体射血分数（LAEF）、左房被动射血分数(LAEF_passive)、左房主动射血分数(LAEF_active)。对以上容积及射血量数据均经体表面积（BSA）校正,得到左房最大容积指数(LAV_maxI)、左房最小容积指数(LAV_minI)、左心房收缩前容积指数(LAV_preI)、左房总射血容量指数（TASVI）、左房被动射血容量指数（PASVI）、左房主动射血容量指数（AASVI）,分析上述数据与二尖瓣口面积（MVA）的相关性。结果 （1）MS组LAVmaxI、LAVminI、LAV_preI均高于对照组（P<0.05）;（2）MS组TASVI、PASVI、AASVI与对照组差异无统计学意义（P>0.05）;（3）MS组LAEI、LAEF、LAEFpassive、LAEF_active均低于对照组（P<0.05）;（4）MS组LAV_maxI、LAV_minI、LAV_preI、LAEF、LAEFpassive与MVA相关（r=-0.432、-0.421、-0.440、0.352、0.401,P<0.05）,TAVSI、PASVI、AASVI、LAEI、LAEF_active与MVA无相关性（P>0.05）。结论风湿性心脏病MS患者左房存储器功能、管道功能、泵功能均降低。RT-3DE可评价风湿性心脏病MS窦性心律患者左房功能。更多还原

【Abstract】 Objective To evaluate of left atrial（LA） function in patients with rheumatic mitral stenosis（MS） by real time three-dimensional echocardiography（RT-3DE）.Methods Thirty patients with MS and 50 healthy volunteers underwent RT-3DE.The left atrial end-diastolic volume(LAV_max),end-systolic volume(LAV_min)and pre-systolic volume(LAV_pre)were measured to calculate the total,passive and active atrial stroke volume（TASV,PASV,AASV）,left atrial expansion index（LAEI）,left atrial total,passive,active ejection fraction(LAEF,LAEF_passive,LAEF_active).The volume data were corrected by body surface area（BSA）to get the left atrial end-diastolic volume index(LAV_maxI),end-systolic volume index(LAV_minI),pre-systolic volume index(LAV_preI) and the total,passive and active atrial stroke volume index（TASVI,PASVI,AASVI）.The correlations between the LA volume,stroke volume,function indices and the mitral valve area（MVA）were analyzed.Results（1）LAV_maxI,LAV_minI and LAV_preI were significantly greater in patients with MS than the controls（all P<0.05）.（2）There was no significant difference in TASVI,PASVI and AASVI between the two groups（all P>0.05）.（3）LAEI,LAEF,LAEF_passiveand LAEF_active were significantly lower in patients with MS than the controls（all P<0.05）.（4）There was a significant correlation between the LAV_maxI,LAV_minI,LAV_preI,LAEF,LAEF_passiveand MVA（r=-0.432,-0.421,-0.440,0.352,0.401,all P<0.05）,there was no correlation between the TAVSI,PASVI,AASVI,LAEI,LAEF_activeand MVA（all P>0.05）.Conclusion LA function in patients with mitral stenosis decreased.RT-3DE can be used to evaluate LA function in patients with MS and sinus rhythm.更多还原