【摘要】 目的:对影响重症监护室急性肾损伤(acute kidney injury,AKI)患者预后因素进行分析。方法:选取在重症监护室进行治疗的重症患者384例,选取发生急性肾脏损伤患者100例为观察组,选取未发生急性肾损伤患者100例为对照组,进行对比,分析其影响预后因素。结果:在我院重症监护室内发生急性肾损伤的比例为26.0%,其中肾前性71例(71.0%);肾性23例(23.0%);肾后性6例(6.0%)。在急性肾损伤患者中,ICU住院时间、28 d病死、慢性肺病、手术、脓毒血症、机械通气的比例和基础肌酐值与未发生急性肾损伤患者对比均增加(P﹤0.05)logistic回归分析结果显示慢性肺病、脓毒症、手术、机械通气、基础肌酐值为影响急性肾损伤患者预后的危险因素。结论:对于存在上述危险因素的患者应给予重视,积极干预,采取有效治疗,从而降低病死率。更多还原

【Abstract】 Objective: To analyze the factors influencing the prognosis of patients with acute kidney injury( AKI) in intensive care unit( ICU). Methods: 384 patients in the ICU were selected for the study,including 100 cases of AKI,and other 100 cases without AKI to be compared,the factors influencing the prognosis analyzed. Results: The proportion of AKI in the ICU was 26. 0 %,among which there were 71 cases of prerenal failure( 71. 0 %),23 cases of renal neutral failure( 23. 0 %) and 6 cases of postrenal failure( 6. 0 %). Compared with patients without AKI,ICU hospital stay,the proportion of 28 days mortality,chronic lung disease,surgery,sepsis,mechanical ventilation,creatinine value were increased,difference was statistically significant( P ﹤ 0. 05). Logistic regression analysis showed that chronic lung disease,sepsis,surgery,mechanical ventilation,the basic creatinine value were risk factors of AKI prognosis. Conclusion: Patients with these risk factors should be given full consideration,actively intervened and treated with effective measures to reduce mortality.更多还原