【摘要】 目的:探讨妊娠合并血小板减少的病因和围产期的处理。方法:回顾性分折49例妊娠合并血小板减少的临床资料,妊娠相关性血小板减少(pregnancy-associated thrombocytopenia,PAT)30例(61.2%)为PAT组,妊娠合并高血压病(pregnancy with hypertension,PHD)9例(18.4%)为PHD组,免疫性血小板减少症(immune thrombocytopenia,ITP)7例(14.3%)为ITP组,其他组3例(6.1%)。结果:PAT组和PHD组产后血小板计数均恢复至正常水平,与妊娠期比较差异有统计学意义(P<0.05);ITP组与其他组产后血小板计数均升高,但与妊娠期比较差异无统计学意义(P>0.05)。结论:妊娠合并血小板减少以PAT多见,病情轻,预后良好,其次为PHD、ITP和其他血液病,临床应根据产妇血小板减少的程度和产科特征,采取个体化治疗,以保母婴安全。更多还原

【Abstract】 Objective: To investigate the cause of thrombocytopenia in pregnancy and the treatment of perinatal stage. Methods: The clinical data of 49 cases of pregnant women with thrombocytopenia was retrospectively analyzed. Of 49 cases,30 patients( 61. 2 %) were pregnancy-associated thrombocytopenia( PAT),9 patients( 18. 4 %) with hypertension( PHD),7 patients( 14. 3 %) with immune thrombocytopenia( ITP),and 3 patients( 6. 1 %) with other etiologies. Results: Postpartum platelet count of PAT group and PHD group were restored to normal levels.There was statistically significant difference compared with pregnancy( P ﹤ 0. 05). Postpartum platelet count of ITP group and others were improved,but the difference was not statistically significant compared with pregnancy( P > 0. 05). Conclusion: Gestational thrombocytopenia is mostly present with PAT,which is mild and has good prognosis. PHD,ITP,and other blood diseases are the following common occurrence. Therefore,it should be considered to take individual therapy according to the degree of maternal thrombocytopenia and obstetric characteristics,to ensure the safety of both mothers and children.更多还原