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非离子型对比剂对肾功能的影响

Clinical influence of non-ionic contrast agents on renal function

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【作者】 甘璐尤燕舞王立学李清锋胡带翠陆皓

【Author】 GAN Lu;YOU Yanwu;WANG Lixue;LI Qingfeng;HU Daicui;LU Hao;The Affiliated Hospital of Youjiang Medical College for Nationalities;

【机构】 广西右江民族医学院附属医院

【摘要】 目的:探究200名行CT血管造影术检查的患者使用非离子型对比剂对肾脏的临床影响。方法:选取在我院治疗的200例行64排CT血管造影检查的患者,将其随机分为观察组和对照组,各100例,其中观察组患者在行造影术前采取预防措施,对照组未采取预防措施。结果:对照组患者的对比剂肾病发病率及不良反应发生率高于观察组(P<0.05);对照组患者术后血清肌酐值高于术前(P<0.05),术后估算的肾小球滤过率低于术前(P<0.05)。结论:临床使用非离子型对比剂时应注意对患者的身体状况进行全面检查,采取有效的预防措施,以减少对比剂肾病等并发症的发生率。

【Abstract】 Objective: To explore the clinical influence of non-ionic contrast agents on kidneys of 200 patients that underwent CT angiography examination. Methods: 200 patients were chosen and randomly divided into the observation group and the control group,with 100 cases in each group. Preventive measures were taken before angiography in the observation group but not in the control group. Results: The morbidity rate of contrast nephropathy and adverse effects in the control group were higher than those in the observation group( P < 0. 05); the postoperative value of serum creatinine( Scr) was higher than preoperative one of Scr in the control group( P < 0. 05); the estimated postoperative glomerular filtration rate( e GFR) was lower than preoperative one( P < 0. 05). Conclusion: While non-ionic contrast agents are used for CT angiography,the patients must be examined thoroughly and effective measures must be taken so that the morbidity rate of complications such as contrast nephropathy will be reduced.

  • 【文献出处】 包头医学院学报 ,Journal of Baotou Medical College , 编辑部邮箱 ,2016年08期
  • 【分类号】R816.7
  • 【下载频次】29
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