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PET/CT对腮腺偶发性18F-FDG高摄取灶的诊断价值

Diagnosis value of PET/CT in the patients with incidental 18F-FDG uptake in the parotid glands

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【作者】 周硕林美福陈文新陈国宝李君霞陈彩龙

【Author】 ZHOU Shuo;LIN Meifu;CHEN Wenxin;CHEN Guobao;LI Junxia;CHEN Cailong;Department of Nuclear Medicine of Provincial Clinical Hospital of Fujian Medical University;

【机构】 福建医科大学省立临床医学院福建省立医院核医学科PET-CT中心

【摘要】 目的:探讨PET/CT(应可直接使用)对腮腺偶发性18F-FDG高摄取灶的诊断价值。方法:回顾性分析2009年2月至2014年2月38例经病理或临床随访证实的腮腺偶发性18氟-脱氧葡萄糖(18F-FDG)高摄取灶患者PET/CT资料。结果:38例腮腺偶发性18F-FDG高摄取灶患者中,12例患者的病灶为恶性(均为腮腺外恶性病变转移、浸润)、13例患者为良性,其中多形性腺瘤8例、Warthin’s瘤4例、炎性肉芽肿1例,另有13例病灶经1年随访复查为良性病变;良、恶性病变患者年龄、性别差异间比较无统计学意义(P>0.05),腮腺外存在恶性病变患者腮腺18F-FDG高摄取灶为恶性病变的危险性更高(x2=13.74,P<0.05),腮腺良、恶性病灶的SUV值、增强后CT值间比较差异无统计学意义(P>0.05)。结论:恶性肿瘤患者的腮腺偶发性18F-FDG高摄取灶为恶性病变的可能性较高,而SUV值及CT所见不能有效鉴别腮腺良、恶性病灶。

【Abstract】 Objective: To evaluate the clinical significance of PET/CT in the diagnosis of the patients with incidental 18F- FDG uptake in the parotid glands. Methods: PET/CT data of 38 cases with incidental 18F- FDG uptake in the parotid glands from February 2009 to February 2014 in our hospital were retrospectively analyzed in the study. All of the patients were confirmed by histopathology or imaging follow- up. Results: Among 38 patients with incidental 18F- FDG uptake in the parotid glands,there were 12 cases of malignant lesions( all metastases) and 13 cases of benign lesions including 8 cases of pleomorphic adenomas,4 cases of Warthin’s tumours and 1 case of benign granulomatous lesion. The other 13 cases of lesions were benign after 1 year imaging follow- up. The age,sex,SUV or enhanced CT findings in patients with benign lesions were not significantly different from those in patients with malignant lesions( P > 0. 05). The presence of other recurrent or metastatic malignant tumors outside of the parotid glands for the patients was correlated with a greater risk of malignancy( χ2= 13. 74,P < 0. 05). Conclusions: Patients with incidental 18F- FDG uptake in the parotid glands have a higher risk of malignant lesions. SUV or enhanced CT could not reliably differentiate malignant from benign incidental parotid lesions.

【基金】 福建省卫生系统中青年骨干人才培养项目(2013-ZQN-JC-4)
  • 【文献出处】 包头医学院学报 ,Journal of Baotou Medical College , 编辑部邮箱 ,2016年01期
  • 【分类号】R739.8
  • 【被引频次】2
  • 【下载频次】52
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