【摘要】 目的探讨¹⁸F-氟代脱氧葡萄糖(¹⁸F-FDG)PET/CT在鼻咽癌分期中的价值。方法回顾性分析35例鼻咽癌患者相关影像学检查资料,分别根据¹⁸F-FDG PET/CT与CT、MR对鼻咽癌患者进行治疗前分期、治疗后再分期,采用Spearman相关性分析全身病灶最大值SUVmax、鼻咽部SUVmax分别与T分期、临床分期的相关性。结果¹⁸F-FDG PET/CT改变了12例治疗前患者的分期,9例治疗后患者的再分期。在再分期的评价中,¹⁸F-FDG PET/CT诊断复发转移的灵敏度为100%（9/9）、特异度55.6%（5/9）、阳性预测值为69.2%（9/13）、阴性预测值为100%（5/5）。全身最高SUVmax与T分期的相关性为0.677（P<0.05）,与临床分期的相关性为0.667（P<0.05）,鼻咽部SUVmax与T分期的相关性为0.71（P<0.05）,与临床分期的相关性为0.46（P<0.05）。结论¹⁸F-FDG PET/CT对鼻咽癌的分期、再分期与临床分期有一定的价值。更多还原

【Abstract】 Objective To investigate the value of¹⁸F-FDG PET / CT in staging of nasopharyngeal carcinoma（ NPC）. Methods Thirty-five patients with nasopharyngeal carcinoma who underwent¹⁸F-FDG PET / CT examination were retrospectively evaluated. The patients were staged according to the results of¹⁸F-FDG PET /CT,CT and MR. The correlations of whole body lesions SUVmaxand nasopharynx SUVmaxwith T stage and clinical stag were analyzed by the Spearman correlation analysis. Results The results of¹⁸F-FDG PET / CT led to changes of the staging in twelve pre-therapeutic patients and nine post-therapeutic patients. In restaging evaluation,the specificity,sensitivity,positive predictive value and negative predictive value of¹⁸F-FDG PET /CT were 100%（ 9 /9）,55. 6%（ 5 /9）,69. 2%（ 9 /13） and 100%（ 5 /5）,respectively. The correlation of whole body lesions SUVmaxwith T staging was 0. 677（ P < 0. 05）,with clinical staging was 0. 667（ P < 0. 05）,nasopharynx SUVmaxwith T staging was 0. 71（ P < 0. 05）,with clinical staging was 0. 46（ P < 0. 05）.Conclusion¹⁸F-FDG PET / CT is valuable in staging, restaging, and clinical staging of patients with nasopharyngeal carcinoma.更多还原