【摘要】 目的:观察0.9%生理盐水代替75%酒精行药物过敏试验局部皮肤清洁的可行性及安全性。方法:采用对照试验的方法,观察0.9%生理盐水局部清洁组221例与75%酒精局部消毒组219例患者行青霉素或头孢硫脒药物过敏试验后假阳性率的情况,建立皮试交接单分析患者皮试部位皮肤有无感染症状。结果:0.9%生理盐水清洁后皮试阳性率与75%酒精消毒后皮试阳性率差异无统计学意义,但两组皮试假阳性率差异有统计学意义(P<0.05)。观察72小时内两组患者皮试局部皮肤均无红、肿、热、痛等感染症状。结论:0.9%生理盐水清洁局部皮肤后行药物过敏试验,假阳性率明显低于75%酒精消毒局部皮肤后行药物过敏试验,0.9%生理盐水替代75%酒精行局部皮肤清洁是安全可行的。更多还原

【Abstract】 Objective:To observe the security and feasibility of using 0.9% normal saline to clean the skin test site instead of 75% alcohol. Methods:Observe the difference in the false positive rates of the controlled trials with 221 cases using 0.9% normal saline and 219 cases using 75% alcohol to disinfect the skin test site in penicillin or cefathiamidine skin tests and set up a form to record infection signs. Results:There is no statistical difference in the positive rates between the control group and the test group, but there are statistically significant differences in the false positive rates(P<0.05).We observed the skin test sites for following 72 hours,no one had local infection signs. Conclusion:The false positive rate of the test group is obviously lower than the control group’s. Using 0.9% normal saline to clean the skin test site is safe and feasible.更多还原