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强心饮治疗左室射血分数正常的慢性心力衰竭临床研究

Clinical Observation on Qiangxin Decoction for Treatment of Chronic Heart Failure with Normal Left Ventricular Ejection Fraction

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【作者】 郭美珠唐丽萍黄国毅张莉娜

【Author】 Guo Meizhu;Tang Liping;Huang Guoyi;Zhang Lina;The Hospital of Integrated Traditional Chinese and Western Medicine in ShangHai Baoshan District;

【机构】 上海市宝山区中西医结合医院上海中医药大学附属曙光医院上海交通大学医学院生物统计学教研室

【摘要】 目的观察强心饮治疗左室射血分数正常的慢性心力衰竭的临床疗效。方法将58例患者随机分为两组,治疗组28例,给予基础治疗加强心饮口服,对照组30例给予基础治疗,10d为一个疗程。观察两组患者治疗前后N末端脑钠肽前体(NT-Pro-BNP)差值占比、心功能、中医证候积分、生活质量积分。结果强心饮有明显改善NT-pro-BNP,提高心功能,改善临床症状,改善生活质量积分的作用。结论强心饮治疗左室射血分数正常的慢性心力衰竭有效与改善NT-pro-BNP含量有关。强心饮疗效确切,服用安全,无不良反应。

【Abstract】 Objective To evaluate the effect of Qiangxin decoction(QXD)for treatment of chronic heart failure(CHF)patients with normal left ventricular ejection fraction(LVEF).Methods Fifty-eight CHF patients with normal LVEF were randomly divided into two groups:The control group(n =30)treated with routine treatment,and the treatment group(n =28)treated with QXD in the basis of routine treatment for 10 days.The N-terminal pro-brain natriuretic peptide(NT-proBNP)level,cardiac function,integration of TCM syndrome and life quality score were observed.Results The NT-proBNP,cardiac function,integration of TCM syndrome and life quality were improved.Conclusion QXD is effective in treating CHF patients with LVEF,which can improve NT-proBNP.

【基金】 上海市卫生局基金资助项目(No.ZYSNXD011-RC-XLXX-20110002)
  • 【文献出处】 中西医结合心脑血管病杂志 ,Chinese Journal of Integrative Medicine on Cardio-/Cerebrovascular Disease , 编辑部邮箱 ,2015年11期
  • 【分类号】R259
  • 【被引频次】4
  • 【下载频次】135
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