【摘要】 目的:观察阿仑磷酸钠联合金天格胶囊治疗绝经后骨质疏松(PMOP)的临床疗效。方法:98例PMOP患者随机分为阿仑磷酸钠片组(阿仑磷酸钠片70 mg,po,每周1次)32例、金天格胶囊组(1.2 g,po,tid)32例和联用组(阿仑磷酸钠片70mg,po,每周1次+金天格胶囊1.2 g,po,tid)34例,连续治疗6个月,比较3组患者治疗前后的临床症状评分、骨密度(BMD)、血钙、血磷、碱性磷酸酶(AKP)及肝肾功能等各项指标的变化数据。结果:治疗6个月后,联用组症状评分下降幅度明显优于阿仑磷酸钠片组和金天格胶囊组(P<0.05);3组的BMD均较治疗前明显上升,且联用组改善更明显(P<0.05)。结论:阿仑磷酸钠联合金天格治疗PMOP的效果显著,能够有效改善临床症状,明显增加骨密度,值得推广应用。更多还原

【Abstract】 Objective: To explore the clinical effect of alendronate combined with Jintiange capsules in the treatment of postmenopausal osteoporosis( PMOP). Methods: Ninety-eight cases of PMOP patients were randomly divided into three groups. The combination treatment group( 34 cases) was treated with alendronate tablets combined with Jintiange capsules,while the control group A( 32cases) and the control group B( 32 cases) was respectively treated with alendronate tablets and Jintiange capsules,and the treatment course was six months. The changes of the clinical symptom score,bone mineral density( BMD),serum calcium,serum phosphorus,AKP,hepatorenal function and so on before and after the treatment were recorded. Results: After the six-month treatment,the clinical symptom score of the treatment group was much better than that in the two control groups( P < 0. 05). BMD in the three groups was increased after the treatment( P < 0. 05),and the increase in the treatment group was more notable than that in the two control groups( P< 0. 05). Conclusion: Alendronate combined with Jintiange capsules can effectively improve BMD and relieve clinical symptoms in the patients with PMOP,which is worthy of promoted application.更多还原