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血府逐瘀汤联合盐酸胺碘酮注射液治疗急性心肌梗死临床观察

The Clinical Observation of Xuefu Zhuyu Decoction Combined with Amiodarone Hydrochloride Injection on Acute Myocardial Infarction

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【作者】 刘淑云安国辉郝立艾孔令军曹庆艳宗文仓刘丽霞

【Author】 LIU Shuyun;HAO Li′ai;KONG Lingjun;Yutian Hospital of Tangshan,Hebei;

【机构】 河北省唐山市玉田县中医医院河北省唐山市玉田县医院

【摘要】 目的观察血府逐瘀汤联合盐酸胺碘酮注射液治疗急性心肌梗死的临床效果。方法选取520例患者为研究对象,依照治疗方法不同分为观察组和对照组各260例,对照组患者采用盐酸胺碘酮注射液入液静滴,观察组患者给予血府逐瘀汤联合盐酸胺碘酮注射液治疗,分析治疗效果。结果治疗后两组患者红细胞免疫功能评分、血清胱抑素C(CPI)、左室射血分数(LVEF)和肌钙蛋白I水平(c Tn I)水平明显改善(P<0.05),观察组患者免疫复合物花环率(6.94±1.12)%、脑尿钠肽(76.95±3.64)ng/m L显著低于对照组的(9.21±1.27)%、(148.2±2.9)ng/m L(P<0.05);观察组患者LVEF(0.56±0.07)%,显著高于对照组的(0.48±0.04)%(P<0.05);观察组患者Cys C(0.82±0.6)mg/L及c Tn I(2.65±0.02)ng/m L,均显著低于对照组的(1.05±0.7)mg/L、(4.57±0.08)ng/m L(P<0.05);观察组患者治疗总有效率显著高于对照组(P<0.05)。结论在急性心肌梗死患者治疗中联合血府逐瘀汤和盐酸胺碘酮注射液能够改善患者临床表现,提高治疗效果。

【Abstract】 Objective: To observe the clinical effects of Xuefu Zhuyu Decoction combined with Amiodarone hydrochloride injection on acute myocardial infarction. Methods: 520 patients,chosen as the research objects,were divided into the observation group and the control group according to different treatment methods,260 cases in each group. The control group was treated with Amiodarone hydrochloride injection,and the observation group was treated with the combination of Xuefu Zhuyu Decoction and Amiodarone hydrochloride injection. The effects were analzed. Results: After treatment,the red blood cell immune function score,serum cystatin C(CPI),left ventricular shoot ejection fraction(LVEF) and cardiac troponin I(c Tn I) level were improved significantly in both groups(P < 0.05). In the observation group,RBC-ICR was(6.94±1.12)%,BNP(76.9±3.6) ng/m L,obviously lower than(9.21±1.27)% and(148.2±2.9) ng/m L in the control group(P < 0.05). LVEF of the observation group was(0.56±0.07)%,obviously higher than(0.48±0.04)% in the control group(P < 0.05). Cys C of the observation group was(0.82±0.6) mg/L and c Tn I was(2.65±0.02)ng/m L,both obviously lower than(1.05±0.7) mg/L,(4.57±0.08) ng/m L in the control group(P < 0.05). The total effective rate of the observation group was 93.1%,obviously higher than 75.9% in the control group(P < 0.05). Conclusion: Xuefu Zhuyu Decoction combined with Amiodarone hydrochloride injection on patients with acute myocardial infarction can improve the clinical performance and the treatment effect,with the application value.

【基金】 河北省唐山市科技局指导性项目(131302109a)
  • 【文献出处】 中国中医急症 ,Journal of Emergency in Traditional Chinese Medicine , 编辑部邮箱 ,2015年12期
  • 【分类号】R542.22
  • 【被引频次】14
  • 【下载频次】94
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