【摘要】 目的观察3种不同治疗方案治疗重症手足口病(HFMD)的临床疗效。方法选取214例HFMD患者,随机分为西医组75例、西医加热毒宁组75例、西医加羚角钩藤汤组64例,3组均给予西医对症治疗,其余两组加用热毒宁注射液、羚角钩藤汤,连用3~5 d,观察体温消退时间、皮疹消退时间及不良反应等情况。结果西医加羚角钩藤汤组和西医加热毒宁组在退热方面较西医组疗效明显(P<0.05);西医加热毒宁组与西医联合羚角钩藤汤组退热时间相当(P>0.05)。在皮疹消退方面,西医加羚角钩藤汤组和西医加热毒宁组在皮疹消退方面较西医组疗效明显(P<0.05);西医加热毒宁组与西医加羚角钩藤汤组皮疹消退时间相近(P>0.05)。结论西医加热毒宁组、西医加羚角钩藤汤两组临床疗效均优于单纯西医组,且不良反应少,安全有效。更多还原

【Abstract】 Objective: To observe the clinical effects of three different kinds of treatments on severe HFMD.Methods: 214 cases with HFMD were chosen and divided into the western medicine group(75 cases),the western medicine with Reduning Injection group(75 cases) and the western medicine plus Lingjiao Gouteng Decoction group(64 cases). Three groups were given symptomatic treatment of western medicine,the other two groups with Reduning Injection and Lingjiao Gouteng Decoction,Continuous 3 ~5 days,observing the temperature subsided,skin rash subsided time,other symptoms and adverse reactions. Results: The curative results showed: compared with the western medicine group,the western medicine and Lingjiao Gouteng Decoction group and the western medicine with Reduning Injection group received a better curative effect on abatement of fever(P < 0.05);the western medicine with Reduning Injection group and the western medicine combined with Lingjiao Gouteng Decoction group had no statistical difference in antifebrile time(P > 0.05). Compared with western medicine group,the western medicine and Lingjiao Gouteng Decoction group and the western medicine with Reduning Injection group received a better curative effect on rash subsided time(P < 0.05);the western medicine with Reduning Injection group and the western medicine plus Lingjiao Gouteng Decoction group had no statistical difference in the rash subsided time(P > 0.05). Conclusion: The clinical efficacies of the western medicine with Reduning Injection group and the western medicine and Lingjiao Gouteng Decoction are better than that of the western medicine group with less adverse reactions,safe and effective,worthy of clinical promotion.更多还原