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清热解毒法对急性冠脉综合征患者血脂及血清指标的影响
Clinical Study on Blood Lipid and Serum Index of Patients with Acute Coronary Syndrome Treated with Detoxification
【摘要】 目的观察清热解毒法治疗急性冠脉综合征对患者血脂和血清指标的影响。方法选取急性冠脉综合征患者150例,随机分为两组。对照组71例,给予阿托伐他汀治疗;观察组79例,在对照组基础上加用清热解毒方进行治疗。分别于治疗前后测定两组患者总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDLC)、高密度脂蛋白胆固醇(HDL-C)、血浆脂联素(APN)、超敏C反应蛋白(hs-CRP)水平并进行比较。结果治疗后观察组TC、TG、LDL-C、hs-CRP水平均明显低于对照组,HDL-C、APN水平明显高于对照组(P<0.05)。结论以清热解毒法辅助治疗急性冠脉综合征,对于改善患者血脂水平,抑制炎症反应有着积极而有效的作用,其临床效果优于单纯西医治疗者。
【Abstract】 Objective: To investigate the effect of detoxification treatment on the blood lipid and serum index of patients with acute coronary syndrome,and find effective treatment. Methods: 150 cases of patients with acute coronary syndrome were randomly divided into two groups. The control group with 71 cases were given atorvastatin therapy;the observation group with 79 cases,based on the treatment of the control group,received extra detoxification treatment. Two groups of patients were measured the levels of TC,TC,TG,LDL-C,HDL-C,APN,hs-CRP and compared before and after treatment. Results: Before treatment,in both group,the differences among the levels of blood lipids,ANP,and hs-CRP were not statistically significant. After treatment,the levels of TC,TG,LDLC,HDL-C,APN,hs-CRP in the control group were respectively(5.10 ±0.52) mmol/L,(1.98 ±0.13) mmol/L,(2.14 ±0.27) mmol/L,(1.31 ±0.17) mmol/L,(8.73 ±0.88) mg/L,(4.86 ±0.47) mg/L,while the observation group were(4.39±0.48) mmol/L,(1.88±0.15) mmol/L,(1.97±0.15) mmol/L,(1.42±0.18) mmol/L,(13.19±1.06) mg/L,(2.10 ±0.23) mg/L. TC,TG,LDL-C,hs-CRP of the observation group were significantly lower than those of the control group,while levels of HDL-C,APN were significantly higher,with statistically significance(P < 0.05).Conclusion: The method of assisted detoxification treatment on acute coronary syndrome,has an improvement in the patient’s blood lipids,and positively inhibit inflammation,whose clinical effect is better than that of the Western medicine treatment.
- 【文献出处】 中国中医急症 ,Journal of Emergency in Traditional Chinese Medicine , 编辑部邮箱 ,2015年07期
- 【分类号】R259
- 【被引频次】5
- 【下载频次】56