【摘要】 目的观察补肾益聪颗粒治疗肝肾阴虚型轻度血管性认知功能障碍(m VCI)的临床疗效。方法将符合纳入标准的156例m VCI患者按就诊顺序获得选取的随机数字,再对随机数字进行处理,分成3组,安理申组(A组)、补肾益聪颗粒组(B组)和安理申合补肾益聪颗粒组(C组),疗程为3个月。观察3组治疗前后简易精神状态检查量表(MMSE)、日常生活能力量表(ADL)、蒙特利尔认知评估量表(Mo CA)及血液流变学的改变。结果 3组患者MMSE、ADL、Mo CA积分及血液流变学均改善,B、C两组较A组改善明显,C组改善优于B组,差异有统计学意义(P<0.05)。结论补肾益聪颗粒可以改善肝肾阴虚型m VCI患者的临床症状,为治疗肝肾阴虚型m VCI患者的有效药物。更多还原

【Abstract】 Objective: To observe the effect of Bushen Yicong Keli in treatment of patients with mild vascular cognitive impairment(m VCI) of deficiency syndrome of the liver-yin and kidney-yin.Methods: 156 patients with m VCI were divided into 3 groups: A group treated with Aricept,B group treated with Bushen Yicong Keli,C group treated with Aricept and Bushen Yicong Keli.The treatment time was 3 months.The scores of mini-mental state examination(MMSE) smart scale,the activity of daily living(ADL) scale and Montreal Cognitive Assessment(Mo CA) were calculated.The level of hemorheological was tested.Results: The scores of ADL,MMSE and MoCA were improved significantly in all 3 groups.The level of hemorheological were all reduced.Compared with A group,group B and C were improved more significantly.The difference was statistically significant(P < 0.05).Conclusion: Bushen Yicong Keli could improve clinical symptoms in patients with m VCI of deficiency syndrome of the liver-yin and kidney-yin.更多还原