【摘要】 目的了解四川省绵阳市预防接种异常反应(AEFI)的发生特征,评价AEFI监测系统运转情况,分析其影响因素,提高监测的敏感性。方法利用excel对2009—2013年绵阳市AEFI数据进行描述性分析。结果该市共使用疫苗44种,接种6 632 472剂次,报告发生AEFI的共26种疫苗548例,报告发生率为8.26/10万剂。以一般反应为主,占报告总数的77.56%;无细胞百白破疫苗(DTa P)反应人数最多,占报告总数的29.38%。AEFI的发生和接种针次与年龄有关,0~2岁病例数最多,反应时间主要集中在当日和次日,占报告总数的81.57%。临床诊断主要以发热、红肿、硬结和过敏性皮疹最为多见,占总报告数的81.21%。结论该市AEFI主要发生于DTa P,以一般反应为主;近年来该市AEFI监测敏感性不断提高。更多还原

【Abstract】 [Objective]To understand the incidence features of Adverse Events Following Immunization(AEFI),to evaluate the operation of AEFI surveillance system,to analyze its influencing factors,and improve sensitivity of monitoring. [Methods]Excel was used to descriptively analyzed the AEFI data of Mianyang City from 2009-2013.[Results]A total of 44 kinds of vaccine were used in Mianyang City,with 6 632 472 times of vaccination,Among which 548 AEFI cases were reported,involving 26 kinds of vaccine,the reported incidence rate was 8.26/100 000. Most AEFI cases had general reaction,accounting for 77.56%,29.38%induced by DTa P vaccine. The occurrence of AEFI was related with the times of vaccination and age,most cases were 0-2 years old children. The reaction time concentrated in the day and the next day,accounting for 81.57%. The most symptoms were fever,redness,induration,and allergic rashes,accounting for 81.21%.[Conclusion]The occurrence of AEFI is mainly caused by DTa P vaccine,with the general reaction. The sensitivity of AEFI surveillance has been improved in recent years in this city.更多还原