【摘要】 目的:探讨复方丹参注射液联合西药治疗冠心病心绞痛患者临床疗效观察及对患者血脂水平的影响。方法:冠心病心绞痛患者188例根据随机分组方法随机分为对照组和治疗组,各94例。对照组采用西药治疗,治疗组在西药基础上结合复方丹参注射液治疗。对比分析两组心绞痛症状疗效、心电图疗效、血脂水平、心绞痛发作持续时间和发作次数及不良反应发生情况。结果:治疗组心绞痛症状总有效率(91.49%)显著高于对照组(78.72%)(P<0.05);治疗组心电图总有效率(85.11%)显著高于对照组(70.21%)(P<0.05);治疗组LDL-C、TC、TG水平治疗后显著低于治疗前(P>0.05),而HDL-C水平治疗后显著高于治疗前(P>0.05);治疗组LDL-C、TC、TG水平治疗后显著低于对照组(P>0.05),而HDL-C水平治疗后显著高于对照组(P>0.05);两组心绞痛发作持续时间治疗后显著短于治疗前(P<0.05),发作次数显著少于治疗前(P<0.05);治疗组心绞痛发作持续时间治疗后显著短于对照组(P<0.05),发作次数显著少于对照组(P<0.05);治疗期间均未见明显不良反应。结论:复方丹参注射液联合西药治疗冠心病心绞痛患者临床疗效显著,改善患者血脂代谢。更多还原

【Abstract】 Objective: To evaluate the clinical efficacy of Compound Danshen Injection combined with Western medicine in patients with angina pectoris and its effect on blood lipid levels. Methods: 188 cases of patients with angina pectoris were randomly divided into control and treatment groups based on the randomization method,94 cases in each. The control group was treated with western medicine and the treatment group combined the Western medicine and the Compound Danshen Injection. We compared the efficacy,ECG,blood fat levels,angina attack frequency and duration and adverse events. Results: The total efficiency of the angina symptoms in the treatment group(91. 49%) was significantly higher than the control group’s(78. 72%)(P < 0. 05). The total efficiency of the treatment group electrocardiogram(85. 11%)was significantly higher the contronl group’s(70. 21%)(P < 0. 05). The treatment group’s LDL-C,TC and TG levels after treatment were significantly lower than those before treatment(P > 0. 05),but HDL-C level higher than that before treatment(P > 0. 05). The treatment group’s LDL-C,TC and TG levels after treatment were significantly lower than those of the control group(P > 0. 05) while HDL-C levels were significantly higher(P > 0. 05). The two groups’ angina pectoris duration was significantly shorter after treatment(P < 0. 05) and the number of attacks was significantly small(P< 0. 05). The treatment group’s angina duration after treatment was significantly shorter than that of the control group(P< 0. 05) and the attacks were significantly less than the control group’s(P < 0. 05). There was no obvious adverse reaction. Conclusion: The clinical efficacy of Compound Danshen Injection combined with Western medicine treatment of angina pectoris is significant in lipid metabolism.更多还原