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降钙素原水平检测对鉴别重症监护病房血流感染患者菌种的作用

Role of Calcitonin Original Level Testing in Identifying Strains of Bloodstream Infections of Patients in ICU

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【作者】 龚剑锋向镜芬杨祥孟启勇雷伟健

【Author】 GONG Jian-feng;XIANG Jing-fen;YANG Xiang;The Fifth Hospital of Ji’nan University,The People’s Hospital of Qingyuan City;

【机构】 暨南大学第五医院清远市人民医院

【摘要】 目的:探讨PCT水平对鉴别重症监护病房血流感染患者菌种的价值。方法:选择2011年3月-2014年1月本院ICU患者131例作为研究对象,按照其菌种将其分为G-组、G+组及真菌组,比较各组PCT水平差异,并根据其ROC曲线判断血清PCT的诊断性能。结果:三组血清PCT中位数水平差异具有统计学意义(P<0.05);血清PCT水平对G-菌与G+菌及真菌所致的血流感染鉴别诊断性能较高。结论:血清PCT水平对于鉴别G-菌与G+菌或真菌引起的血流感染有一定的临床鉴别价值,但是对于G+菌与真菌引起的感染鉴别意义尚不明确。

【Abstract】 Objective: To investigate the value of calcitonin original level in identifying bacterial bloodstream infections of patients in intensive care unit. Method:131 patients in ICU of our hospital from March 2011 to January 2014 were selected as the objects.They were divided into group G-,group G+ and group fungi according to different strains.Differences in PCT levels were compared among the three groups and diagnostic performance of serum PCT was determined according to its ROC curve.Result:Differences in median serum PCT levels of the three groups were statistically significant.Serum PCT level has a higher diagnostic capacity in differentiating bloodstream infections caused by G- bacteria and G+ bacteria or fungi.Conclusion:Serum PCT level plays a certain role in differentiating bloodstream infections caused by G- bacteria and G+ bacteria or fungi,but it plays an uncertain role in differentiating infections caused by G+ bacteria and fungi.

【基金】 国家自然科学基金资助项目(81102873)
  • 【文献出处】 中国医学创新 ,Medical Innovation of China , 编辑部邮箱 ,2015年22期
  • 【分类号】R515
  • 【被引频次】2
  • 【下载频次】62
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