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90例小儿手足口病血清CK-MB、cTnT及PA变化和临床意义探讨

Clinical Significance Discussion of Serum CK-MB, cTnT and PA Changes in the 90 Children with Hand Foot Mouth Disease

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【作者】 陈召金潘伟权黄敏辉麦坚凝陶建平

【Author】 CHEN Zhao-jin;PAN Wei-quan;HUANG Min-hui;The Qishi Hospital of Dongguan;

【机构】 广东省东莞市企石医院广州市妇女儿童医疗中心

【摘要】 目的:探讨小儿手足口病血清CK-MB、cTnT及PA变化的临床意义。方法:选取本院2012年3月-2014年3月进行诊治的手足口病患儿213例,进入本研究90例,选取45例重症患者为重症组,45例普通患者为普通组,同时选取健康儿童45例为对照组,分别于入院次日、治疗8d后次日抽取静脉血,比较三组儿童CK-MB、cTnT及PA水平变化。结果:三组患者入院次日CK-MB值、cTnT比较,差异具有统计学意义(P<0.05);治疗8d后,三组患者CK-MB值、cTnT均较前下降,比较差异具有统计学意义(P<0.05)。结论:血清CK-MB、cTnT变化提示患儿可存在心肌损伤,PA变化对于判断病情程度及评估预后有指导意义。

【Abstract】 Objective: To explore the clinical significance of serum CK-MB, cTnT and PA in the assessment of the illness in children with hand foot and mouth disease. Method: 213 children with hand, foot and mouth disease treated from March 2012 to March 2014 in our hospital were selected, 90 cases in this study who were divided into severe critical group(45 cases), and ordinary group(45 cases), 45 patients with normal and healthy were selected as control group, respectively, extracted the venous blood from the three groups of children for CK-MB, cTnT and PA level changes in the day after admission and 8 days later. Result: Three groups admitted to hospital with CK-MB value, cTnT statistically significant difference; 8 days after treatment, patients in the three groups of CK-MB value and cTnT were the previous fall, statistically significant difference(P<0.05). Conclusion: The serum CK-MB and cTnT changes suggest the existence of myocardial damage of children who can be, PA is for the diagnosis and evaluation of prognosis.

【关键词】 CK-MBcTnTPA手足口病小儿
【Key words】 CK-MBcTnIPAHand foot and mouth diseaseChildren
【基金】 广东省医学科研基金立项项目(A2007308)
  • 【文献出处】 中国医学创新 ,Medical Innovation of China , 编辑部邮箱 ,2015年22期
  • 【分类号】R725.1
  • 【被引频次】4
  • 【下载频次】32
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