【摘要】 目的:探讨肌红蛋白对心肌梗死型冠心病早期诊断的价值。方法:用免疫比浊法测定310例冠心病患者的肌红蛋白浓度,包括130例急性期入院的心肌梗死型冠心病患者、80例不稳定型心绞痛患者及100例非心肌梗死型冠心病组的结果。结果:心肌梗死型冠心病患者中48例冠脉再通后(45.0±18.2)min出现高峰值,平均为(888.7±47.0)μg/L,与治疗前肌红蛋白(534.3±197.6)μg/L比较差异有统计学意义(P<0.05);肌红蛋白异常持续(37.8±6.3)h。不稳定型心绞痛患者疼痛发作期和间歇期肌红蛋白分别为(55.8±21.4)μg/L和(40.9±12.0)μg/L,自身比较差异有统计学意义(P<0.01)。100例非心肌梗死型冠心病组活动开始前肌红蛋白浓度为(33.8±12.0)μg/L,活动后为(45.8±20.9)μg/L,前后比较差异有统计学意义(P<0.01)。不稳定型心绞痛组和非心肌梗死型冠心病组与心肌梗死型冠心病组入院肌红蛋白比较差异均有统计学意义(P<0.05)。结论:肌红蛋白是心肌梗死型冠心病急性期诊断有效生化指标,有助于与不稳定型心绞痛的鉴别,严格控制好高血压、高血脂、血脑卒的临床指标,便于心肌梗死型冠心病及不稳定型心绞痛病的预防及治疗。更多还原

【Abstract】 Objective:To explore the value of myoglobin in early diagnosis of myocardial infarction-induced coronary heart disease.Method:The myoglobin concentration of 310 patients with coronary heart disease was determined by immune turbidimetry,including 130 patients with myocardial infarction-induced coronary heart disease hospitalized during acute phase,80 cases patients with unstable angina and 100 patients with coronary heart disease of nonmyocardial infarction.Result:The peak value of 48 patients undergoing coronary artery recanalization(45.0±18.2)min with average value at(888.7±47.0)μg/L(P<0.05),average myoglobin before treatment hit(534.3±197.6)μg/L,and the statistical difference was remarkably significance(P<0.05).Myoglobin abnormalities continued(37.8±6.3) h.The attack period and intermittent period in patients with unstable angina of myoglobin hit(55.8±21.4)μg/L and(40.9±12.0)μg/L respectively,the comparative self difference was statistically significant(P<0.01) before the start of activity,the myoglobin concentration of 100 patients with myocardial infarction-induced coronary heart disease group hit(33.8±12.0)μg/L,and that value hit(45.8±20.9)μg/L,the comparative difference before and after activity was statistically significant(P<0.01).Comparative differences in myoglobin between instable angina group,exercise group and myocardial infarction group of coronary heart disease were statistically significant(P<0.05).Conclusion:The myoglobin is an effective diagnosis biochemical index of myocardial infarction-induced coronary heart disease in acute period,and it contributes to the identification of unstable angina,strict control over clinical indexes including the hypertension,high cholesterol and cerebral apoplexy type,being contributable to the prevention and treatment of myocardial infarctioninduced coronary heart disease and unstable angina.更多还原