Objective: To summarize the research progress in therapeutic drug monitoring( TDM) and rational use of anti-tumor drugs,and to provide references for clinical practice. Methods: Research papers were searched with therapeutic drug monitoring,anti-tumor drugs,drug interaction,individual treatmentandrational drug useas key words,and 17 papers were finally screened out according to the inclusion criteria as follows: study of TDM and rational drug use; clinical application and rational use of anti-tumor drugs; a...
【更新日期】
2015-09-14
【分类号】
R969.3
【正文快照】
治疗药物监测(therapeutic drug monitoring,TDM)是指在临床进行药物治疗过程中,观察药物疗效的同时,定时采集患者的体液(如血液、尿液、唾液等),测定其中的药物或其代谢产物的浓度,探讨药物在体内的生物转化过程以及药物浓度的安全范围,并以药动学和药效学理论为基础,借助先进