Objective:To observe the effects of water extract of Zuojin Pill(左金丸,ZJP) on inhibiting the growth of human gastric cancer cell line SGC-7901 and its potential mechanism.Methods:Effects of ZJP on SGC-7901 cells growth were determined by 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide(MTT) assay,cell apoptosis and cell cycle were determined by flow cytometry,and apoptosis induction was detected by means of DNA gel electrophoresis.The cellular mechanism of drug-induced cell death was unravel...
【英文摘要】
Objective:To observe the effects of water extract of Zuojin Pill(左金丸,ZJP) on inhibiting the growth of human gastric cancer cell line SGC-7901 and its potential mechanism.Methods:Effects of ZJP on SGC-7901 cells growth were determined by 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide(MTT) assay,cell apoptosis and cell cycle were determined by flow cytometry,and apoptosis induction was detected by means of DNA gel electrophoresis.The cellular mechanism of drug-induced cell death was unravel...
【基金】
Supported by the China Postdoctoral Science Foundation(No.2014M560666)
【更新日期】
2015-12-03
【分类号】
R285
【正文快照】
Despite the steady decline in occurrence,stomach cancer remains the second most commoncancer worldwide■⑴In addition to surgery,a number ofcomplementary and alternative medicines for gastriccancer have been developed in recent years_(2)Oneof the primary
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