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康复新液治疗慢性糜烂性胃炎的Meta分析

Meta analysis of efficacy of Kangfuxin liquid in the treatment of chronic erosive gastritis

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【作者】 陆莉莉王威费素娟

【Author】 LU Li-li;WANG Wei;FEI Su-juan;Medical College of Xuzhou;Department of Gastroenterology,Affiliated Hospital of Medical College of Xuzhou;

【机构】 徐州医学院徐州医学院附属医院消化内科

【摘要】 [目的]系统评价康复新液治疗慢性糜烂性胃炎(CEG)的疗效及安全性。[方法]计算机检索Cochrane library、EMBase、PubMed、中国知网(CNKI)、万方数据库、维普数据库(VIP)中所有关于康复新液治疗CEG的随机对照研究文献,采用Jadad量表对各独立研究进行质量评价并纳入文献,运用Stata 12.0软件进行Meta分析。[结果]12篇文献纳入研究,共计1 487例患者,其中试验组788例,对照组699例。Meta分析结果显示:康复新液治疗CEG的总有效率和复发率均显著优于对照组,差异有统计学意义(P<0.05)。但对幽门螺杆菌根除率和不良反应,2组差异无统计学意义。[结论]康复新液治疗CEG,具有疗效好、安全可靠等优点,在临床上具有良好的应用前景。

【Abstract】 [Objective]To estimate the efficacy and safety of Kangfuxin liquid in the treatment of chronic erosive gastritis.[Methods]Computer-based online was used to retrieve Cochrane library,Embase,PubMed,CNKI,Wanfang data,VIP database.All randomized controlled trial studys which about the Kangfuxin liquid for the treatment of chronic erosive gastritis were collected.Using the Jadad method to evaluate the quality of the studys.Meta analysis was performed to evaluate the data by using stata12.0software.[Results]Twelve articles were included in the study,a total of 1 487 patients,the experimental group was788 cases and the control group was 699 cases.Meta analysis results showed:Kangfuxin liquid in treatment of chronic erosive gastritis,total effective rate and recurrence rate in treatment group were superior to control group,the difference was statistically significant.But for helicobacter pylori eradication rate and adverse reactions,there are no statistically significant differences between the two groups.[Conclusion]For the treatment of chronic erosive gastritis,Kangfuxin liquid has good curative effect and low recurrence rate advantages,indicating agood application prospect in clinic.However,the quantity and quality of the reviewed studies are far from satisfaction,this conclusion has to be further verified by high quality,large scale and double blinded RCTs.

  • 【文献出处】 中国中西医结合消化杂志 ,Chinese Journal of Integrated Traditional and Western Medicine on Digestion , 编辑部邮箱 ,2015年12期
  • 【分类号】R259
  • 【被引频次】10
  • 【下载频次】289
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