【Objective】To assess the feasibility and safety of a femoral transseptal endocardial left ventricular(LV) approach pacing for cardiac resynchronization therapy(CRT) in patients whose transvenous coronary sinus(CS)implantation had failed. 【Methods】Two patients with congestive heart failure who received a femoral transseptal endocardial LV approach pacing for cardiac resynchronization therapy(CRT) between March 2014 and August 2014 were enrolled. After puncture the atrial septum from the right femoral vein, a...