【Objective】To evaluate the effect of propofol on the damage to hippocampal neurons and cognitive function induced by ketamine anesthesia in infant rats.【Methods】Eighty infant SD rats were randomized into normal saline group(group NS), ketamine group(group K), propofol group(group P), propofol plus ketamine group(group P+K). At 6 h after the initial injection, the rats in each group were subdivided into two units: unit A and unit B. In the unit A, the rats were sacrificed and the hippocampus tissues were har...
【基金】
supported by Department of Health of Sichuan Province(No.:090205)
【更新日期】
2015-04-09
【分类号】
R726.1
【正文快照】
Ketamine is widely used in pediatric anesthewas intraperitoneally injected with a volume of 1 mlsia.Recent studies demonstrated ketamine is inju-every two hours in a blind manner for consecutiverious to brain development and thus results in cog-6 h.The an
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