【Objective】To explore the prognostic factors affecting the progression of hormone sensitive metastatic prostate cancer to castration-resistant prostate cancer(CRPC).【Methods】 A total of 50 cases of hormone sensitive metastatic prostate cancers were treated with androgen deprivation therapy(ADT) in Beijing Jishuitan Hospital from June 2006 to June 2014. Their clinical and pathological data were retrospectively collected and they were followed up regularly in the clinic or in the hospital. The statistic softw...