【摘要】 目的探讨布拉氏酵母菌联合三联疗法(雷贝拉唑、阿莫西林、左氧氟沙星)根除幽门螺杆菌(Hp)的疗效。方法 100例慢性胃炎伴幽门螺杆菌感染患者,随机分为对照组和治疗组,各50例。对照组采用三联疗法治疗,治疗组在三联疗法的基础上加用布拉氏酵母菌散口服,疗程均为2周。疗程结束比较两组Hp根除率、不良反应发生率。结果治疗组患者Hp根除率和不良反应发生率与对照组相比,差异均有统计学意义(P<0.05)。结论布拉氏酵母菌可显著减少不良反应发生,并能提高三联疗法的Hp根除率,值得临床推广运用。更多还原

【Abstract】 Objective To explore the curative effect of Saccharomyces boulardii combined with triple therapy(rabeprazole, amoxicillin, levofloxacin) in eradication of helicobacter pylori(Hp). Methods A total of 100 patients with chronic gastritis and helicobacter pylori infection were randomly divided into control group and treatment group, with 50 cases in each group. The control group was treated by triple therapy, and the treatment group received additional oral administration of Saccharomyces boulardii sachets for treatment. The treatment lasted for 2 weeks, and comparisons were made on Hp eradication rate and incidence of adverse reactions between the two groups at the end of the treatment. Results The differences of Hp eradication rate and incidence of adverse reactions between the treatment group and control group had statistical significance(P<0.05). Conclusion Saccharomyces boulardii can reduce adverse reactions, and increase the Hp eradication rate in triple therapy. This method is worth clinical promotion and application.更多还原