【摘要】 目的探讨舟山地区妊娠妇女的孕期各阶段甲状腺激素的影响因素。方法选取孕妇358例,检测各孕期血清甲状腺激素,并进行问卷调查,Logistic回归模型分析甲状腺素异常的影响因素。结果早孕阶段孕妇甲状腺素异常的危险因素主要是孕前吸烟[OR 11.212(95%CI:5.965~19.232)]、中度焦虑等[OR 4.566(95%CI:2.128~8.612)](P<0.01或P<0.05);中孕阶段孕妇甲状腺素异常的危险因素主要是孕前吸烟[OR 4.123(95%CI:3.313~5.489)]、轻度焦虑[OR 5.335(95%CI:3.254~9.363)]、中度焦虑等[OR 7.151(95%CI:4.259~12.362)](P<0.01或P<0.05);晚孕阶段孕妇甲状腺素异常的危险因素主要是轻度焦虑[OR 7.596(95%CI:2.636~13.585)]、中度焦虑等[OR 5.151(95%CI:1.154~9.541)](P<0.01或P<0.05)。结论孕妇和丈夫戒烟、缓解抑郁和焦虑的情绪,有助于防范和减少本地区孕妇妊娠期甲状腺疾病。更多还原

【Abstract】 Objective To investigate the influence factors on thyroid health conditions during different pregnancy stages of pregnant women in Zhoushan. Methods 358 women were selected and their serum levels of thyroid hormone from different pregnancy stages of pregnant women were detected. The influence factors were analyzed by Binary Logistic Regression.Results Risk factors during early age were mainly associated with smoking before pregnancy[OR 11. 212( 95% CI: 5. 965 ~19. 232) ],anxious with middle degree[OR 4. 566( 95% CI: 2. 128 ~ 8. 612) ]( P < 0. 01 or P < 0. 05); Risk factors during middle age were mainly associated with smoking before pregnancy[OR 4. 123( 95% CI: 3. 313 ~ 5. 489) ],anxious with light degree [OR 5. 335( 95% CI: 3. 254 ~ 9. 363) ],anxious with middle degree[OR 7. 151( 95% CI: 4. 259 ~ 12. 362) ]( P <0. 01 or P < 0. 05); Risk factors during late age were mainly associated with anxious with light degree[OR 7. 596( 95% CI:2. 636 ~ 13. 585) ],anxious with middle degree[OR 5. 151( 95% CI: 1. 154 ~ 9. 541) ]( P < 0. 01 or P < 0. 05). Conclusion Quitting smoking for pregnant woman and her husband,depressing symptoms of anxiety and symptoms are helpful for the prevention of thyroid disease.更多还原